Research Paper Volume 13, Issue 8 pp 11026—11042

Calycosin stimulates the proliferation of endothelial cells, but not breast cancer cells, via a feedback loop involving RP11-65M17.3, BRIP1 and ERα

Schematic illustration of the proposed mechanism by which calycosin promotes the proliferation of ECs and inhibits the growth of BCCs. This selective activity of calycosin in ECs and BCCs depends on a feedback loop involving RP11-65M17.3 and ERα.

Figure 7. Schematic illustration of the proposed mechanism by which calycosin promotes the proliferation of ECs and inhibits the growth of BCCs. This selective activity of calycosin in ECs and BCCs depends on a feedback loop involving RP11-65M17.3 and ERα.