Research Paper Volume 13, Issue 6 pp 8355—8368

90K predicts the prognosis of glioma patients and enhances tumor lysate-pulsed DC vaccine for immunotherapy of GBM in vitro

Combination of 90K and apoptotic U251 cells-pulsed DC vaccine increased the proliferation effect of initial T lymphocytes and altered secretion of related Interleukins. (A) The relative proliferation effects of initial T lymphocytes induced by immature DC, Mature DC, 90K-DC, Apoptosis U251-DC and Apoptosis U251-90K-DC (n=5). (B) The secretion of IL-10 and IL-12p70 induced by the above groups (n=5). * indicates p value

Figure 6. Combination of 90K and apoptotic U251 cells-pulsed DC vaccine increased the proliferation effect of initial T lymphocytes and altered secretion of related Interleukins. (A) The relative proliferation effects of initial T lymphocytes induced by immature DC, Mature DC, 90K-DC, Apoptosis U251-DC and Apoptosis U251-90K-DC (n=5). (B) The secretion of IL-10 and IL-12p70 induced by the above groups (n=5). * indicates p value < 0.05; ** indicates p value < 0.01.