Figure 1. Overlap of this current work’s meta-analysis (Palmer et al.) with the microarray signature of mammalian ageing currently hosted on GenAge (de Magalhães, et al.) ). (A) Gives the overlap for genes overexpressed with age, while (B) gives the overlap for genes underexpressed with age. The p-values given are the result of a hypergeometric test, testing the significance of the given overlap using all other protein-coding genes as a background (i.e. all genes not differentially expressed in the direction of the given analysis).