Research Paper Volume 13, Issue 5 pp 7608—7626

MiR-452-5p promotes colorectal cancer progression by regulating an ERK/MAPK positive feedback loop

MiR-452-5p enhances resistance to 5-FU and reduces CRC apoptosis. (A) Detection of apoptosis in cells transfected with miR-452-5p and miR-452-5p inhibitor together with negative controls. (B) The expression of apoptosis-related proteins detected by western blotting.*p

Figure 3. MiR-452-5p enhances resistance to 5-FU and reduces CRC apoptosis. (A) Detection of apoptosis in cells transfected with miR-452-5p and miR-452-5p inhibitor together with negative controls. (B) The expression of apoptosis-related proteins detected by western blotting.*p < 0.05, **p < 0.01, ***p < 0.001.