Research Paper Volume 13, Issue 6 pp 8510—8523

A novel protein ubiquitination-related five-gene signature predicts overall survival in patients with lung adenocarcinoma

Identification of prognostic E3s/DUBs related DEGs. (A) Veen Diagram for the differentially expressed genes (DEGs)of all samples' whole gene expression with all E3s/DUBs-related genes. (B) Of the 50 E3s/DUBs-related DEGs, 34 were up-regulated, and 16 were downregulated. (C) Heatmap of E3s/DUBs-related DEGs in all samples. (D) Univariate Cox regression analysis showed that 11 genes were associated with overall survival (P

Figure 1. Identification of prognostic E3s/DUBs related DEGs. (A) Veen Diagram for the differentially expressed genes (DEGs)of all samples' whole gene expression with all E3s/DUBs-related genes. (B) Of the 50 E3s/DUBs-related DEGs, 34 were up-regulated, and 16 were downregulated. (C) Heatmap of E3s/DUBs-related DEGs in all samples. (D) Univariate Cox regression analysis showed that 11 genes were associated with overall survival (P<0.1).