Research Paper Volume 13, Issue 7 pp 9582—9591

LCZ696 ameliorates lipopolysaccharide-induced endothelial injury

LCZ696 mitigates lipopolysaccharide (LPS)-induced oxidative stress in HUVECs

Figure 3. LCZ696 mitigates lipopolysaccharide (LPS)-induced oxidative stress in HUVECs. Cells were stimulated with LPS in the presence or absence of LCZ696 (10, 20 μM) for 24 hours. (A). ROS) was measured using DCFH-DA staining; (B). The level of MDA (***P < 0.005 vs. control group; ##, ###P < 0.01, 0.005 vs. LPS group).