Research Paper Volume 13, Issue 6 pp 8880—8894
Integrated analysis of metabolome in a EUS-FNA sample with transcriptome in the TCGA cohort of pancreatic head and body/tail adenocarcinoma
Figure 5. BCAA pathway in pancreatic cancer. (A) metabolites level of BCAA between pancreatic head and body/neck cancer (n=30 for each group). Val and Leu significantly promoted pancreatic cell line proliferation in Ki67 flow cytometry analysis (B) and CCK-8 test (C). Flow cytometry indicated Oxaliplatin treatment for 48 h deceased the rate of apoptosis (D). * p<0.05, ** p<0.005, *** p<0.001.