Research Paper Volume 13, Issue 7 pp 10034—10057

A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients

The association of risk score with OS and clinicopathological characteristics. (A) Kaplan-Meier survival curve analysis of high-risk and low-risk LADC patients from the training set. (B) ROC curves show prediction accuracy of the prognostic signature and AJCC stages in the training set TCGA-LADC patients. (C) Heat map shows association between the expression levels of the five prognostic m6A regulatory genes and clinicopathological characteristics of high- and low-risk LADC patient subgroups. *0.01 ≤ P D) The positive correlation between cancer-related pathways and high-risk LADC patients.

Figure 3. The association of risk score with OS and clinicopathological characteristics. (A) Kaplan-Meier survival curve analysis of high-risk and low-risk LADC patients from the training set. (B) ROC curves show prediction accuracy of the prognostic signature and AJCC stages in the training set TCGA-LADC patients. (C) Heat map shows association between the expression levels of the five prognostic m6A regulatory genes and clinicopathological characteristics of high- and low-risk LADC patient subgroups. *0.01 ≤ P < 0.05, **0.001 ≤ P < 0.01, ***P < 0.001. (D) The positive correlation between cancer-related pathways and high-risk LADC patients.