Research Paper Volume 13, Issue 7 pp 10058—10074

Gut microbiota from mice with cerebral ischemia-reperfusion injury affects the brain in healthy mice

Microbial analyses on the phyla level. (A) Sankey graph showing changes in gut microbial composition on the 15th and 29th day after fecal microbiota transplantation. (B) Percent of community abundance on the phyla level. Firm. means Firmicutes, Bact. means Bacteroidetes, Prot. means Proteobacteria, Verr. means Verrucomicrobia, Acti. means Actinobacteria, Tene. means Tenericutes, Defe. means Deferribacteres. (C) Ratio of Firmicutes and Bacteroidetes on the 15th and 29th days. (D) Principal component analysis (PCA) plot of weighted UniFrac distances showing a clear separation in microbial composition between micecontrol and miceBCCAO. *** denotes P

Figure 1. Microbial analyses on the phyla level. (A) Sankey graph showing changes in gut microbial composition on the 15th and 29th day after fecal microbiota transplantation. (B) Percent of community abundance on the phyla level. Firm. means Firmicutes, Bact. means Bacteroidetes, Prot. means Proteobacteria, Verr. means Verrucomicrobia, Acti. means Actinobacteria, Tene. means Tenericutes, Defe. means Deferribacteres. (C) Ratio of Firmicutes and Bacteroidetes on the 15th and 29th days. (D) Principal component analysis (PCA) plot of weighted UniFrac distances showing a clear separation in microbial composition between micecontrol and miceBCCAO. *** denotes P < 0.001 compared with control mice using a two-way repeated-measures ANOVA with post-hoc Tukey multiple comparisons test. All values are expressed as means ± S.D; n=15.