Research Paper Volume 13, Issue 8 pp 11096—11119

Pan-cancer analysis identifies ITIH1 as a novel prognostic indicator for hepatocellular carcinoma

Association of ITIH1 expression with tumor microenvironment factors. Correlation between ITIH1 expression and immune infiltration of CD8+ T cells (A) and cancer-associated fibroblasts (CAFs) (B) across different cancers in TCGA. (C) Correlation between ITIH1 expression and T cell exclusion signatures, including FAP+ CAFs, myeloid-derived suppressor cells (MDSC), and tumor-associated M2 macrophages (TAM M2) in the TIDE (Tumor Immune Dysfunction and Exclusion) database.

Figure 8. Association of ITIH1 expression with tumor microenvironment factors. Correlation between ITIH1 expression and immune infiltration of CD8+ T cells (A) and cancer-associated fibroblasts (CAFs) (B) across different cancers in TCGA. (C) Correlation between ITIH1 expression and T cell exclusion signatures, including FAP+ CAFs, myeloid-derived suppressor cells (MDSC), and tumor-associated M2 macrophages (TAM M2) in the TIDE (Tumor Immune Dysfunction and Exclusion) database.