Research Paper Volume 13, Issue 7 pp 10158—10174

Hypoxia-induced miR-27 and miR-195 regulate ATP consumption, viability, and metabolism of rat cardiomyocytes by targeting PPARγ and FASN expression

miR-27 and miR-195 were upregulated in hypoxia-exposed cardiomyocytes. (A) Microarray showed the differentially expressed genes in cardiomyocytes under normoxia (N; n = 7) and hypoxia (H,]; n = 7). (B, C) RT-qPCR was performed to show the expression of miR-27 and miR-195 in the isolated cardiomyocytes under normoxia and hypoxia (n = 3). **P

Figure 2. miR-27 and miR-195 were upregulated in hypoxia-exposed cardiomyocytes. (A) Microarray showed the differentially expressed genes in cardiomyocytes under normoxia (N; n = 7) and hypoxia (H,]; n = 7). (B, C) RT-qPCR was performed to show the expression of miR-27 and miR-195 in the isolated cardiomyocytes under normoxia and hypoxia (n = 3). **P < 0.01 vs. the normoxia group.