Research Paper Volume 13, Issue 6 pp 9085—9107

Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients

Higher NID1 expression correlates with increased tumor infiltration of multiple immune cell types. TIMER database analysis shows correlation between NID1 expression levels in LGG (top) and GBM (bottom) patient tissues and tumor infiltration levels of immune cell types, namely, B cells, CD8+ T cells, CD4+T cells, macrophages, neutrophils, and dendritic cells. Each dot corresponds to a glioma patient (LGG or GBM). The blue line represents median levels of tumor-infiltrated immune cells.

Figure 7. Higher NID1 expression correlates with increased tumor infiltration of multiple immune cell types. TIMER database analysis shows correlation between NID1 expression levels in LGG (top) and GBM (bottom) patient tissues and tumor infiltration levels of immune cell types, namely, B cells, CD8+ T cells, CD4+T cells, macrophages, neutrophils, and dendritic cells. Each dot corresponds to a glioma patient (LGG or GBM). The blue line represents median levels of tumor-infiltrated immune cells.