Research Paper Volume 13, Issue 8 pp 11207—11217

Panax notoginseng protects the rat brain function from traumatic brain injury by inhibiting autophagy via mammalian targeting of rapamycin

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Figure 5. Compared with the Panax notoginseng group, there was no significant difference in brain tissue destruction, brain function damage, while mTOR and p-mTOR were significantly decreased in the Panax notoginseng+Rapamycin group. (A) HE staining, Nissl staining and transmission electron microscopy of brain tissue. (B) The neural function defect score at 12h, 24h and 72h. (C) mTOR, p-mTOR, P62, Beclinl, LC3I and LC3II by Western-blotting. n=6.