Research Paper Volume 13, Issue 8 pp 11296—11314

Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

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Figure 1. The hepcidin content is decreased in the postmenopausal women with osteoporosis. (A) Hepcidin concentration in the serum of peripheral blood in the postmenopausal women with osteoporosis (T score ≤ 2.5); (B) Lumbar BMD and serum hepcidin concentration showed a positive linear correlationship in the postmenopausal women with osteoporosis; r = 0.4560; statistical significance was considered at P = 0.0059, (n = 35; age = 62.11 ± 5.9).