Research Paper Volume 13, Issue 8 pp 11296—11314

Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis


Figure 6. Overexpression hepcidin decreases PGC-1β expression in OVX mouse bone. The expression of PGC-1β in bone was evaluated by immunohistofluorescence assays in overexpression hepcidin and non-overexpression hepcidin OVX mouse bone. Scale bar, 50 μm.