Research Paper Volume 13, Issue 8 pp 11411—11432

Investigating the mechanisms of Modified Xiaoyaosan (tiaogan-liqi prescription) in suppressing the progression of atherosclerosis, by means of integrative pharmacology and experimental validation

TGLQ increased the viability of ox-LDL induced macrophages. The viability of macrophages was determined by using a CCK-8 kit. Unlike the macrophages of the control group, the macrophages of the model group, the low-dose TGLQ-serum (LTGLQ) group and the high-dose TGLQ-serum (HTGLQ) group were exposed to 60μg/ml oxidized-LDL (ox-LDL) for 24 h. In addition, control serum, 5% TGLQ serum and 20% TGLQ serum were added to the model group, the LTGLQ group and the HTGLQ group, respectively. #, ##, and ### represent P P P P P P P

Figure 8. TGLQ increased the viability of ox-LDL induced macrophages. The viability of macrophages was determined by using a CCK-8 kit. Unlike the macrophages of the control group, the macrophages of the model group, the low-dose TGLQ-serum (LTGLQ) group and the high-dose TGLQ-serum (HTGLQ) group were exposed to 60μg/ml oxidized-LDL (ox-LDL) for 24 h. In addition, control serum, 5% TGLQ serum and 20% TGLQ serum were added to the model group, the LTGLQ group and the HTGLQ group, respectively. #, ##, and ### represent P < 0.05, P < 0.01, and P < 0.001 respectively, in comparison with the control group. *, **, and *** represent P < 0.05, P < 0.01, and P < 0.001 respectively, in comparison with the model group. %% represents P < 0.01, in comparison with the LTGLQ group.