Research Paper Volume 13, Issue 8 pp 11564—11594

Comprehensive analysis of genomic and immunological profiles in Chinese and Western hepatocellular carcinoma populations

Gene mutations in the four groups. (A) The top 30 most commonly mutant genes in the WCH-HBV-HCC group. (B) The top 30 most commonly mutant genes in the WCH-NonHBV-HCC group. (C) TCGA-HBV- The top 30 most commonly mutant genes in the HCC group. (D) Top 30 most commonly mutant genes in the TCGA-Alcol-HCC group. (E) Hierarchical cluster analysis shows the q value of gene mutations in each group. The screening criteria of genes shown in Figure 2E is: q value F) Gene mutations in the WCH-HBV-HCC group and WCH-NonHBV-HCC group. (G) Gene mutations in the TCGA-Alcol-HCC group and TCGA-HBV-HCC group. (H) Gene mutations in the WCH-HBV-HCC group and TCGA-HBV-HCC group. (I) Gene mutations in the WCH-NonHBV-HCC group and TCGA-Alcol-HCC group. The q values for gene mutations are compared among different groups. Gene mutations with q values

Figure 3. Gene mutations in the four groups. (A) The top 30 most commonly mutant genes in the WCH-HBV-HCC group. (B) The top 30 most commonly mutant genes in the WCH-NonHBV-HCC group. (C) TCGA-HBV- The top 30 most commonly mutant genes in the HCC group. (D) Top 30 most commonly mutant genes in the TCGA-Alcol-HCC group. (E) Hierarchical cluster analysis shows the q value of gene mutations in each group. The screening criteria of genes shown in Figure 2E is: q value <0.1 in at least one group. (F) Gene mutations in the WCH-HBV-HCC group and WCH-NonHBV-HCC group. (G) Gene mutations in the TCGA-Alcol-HCC group and TCGA-HBV-HCC group. (H) Gene mutations in the WCH-HBV-HCC group and TCGA-HBV-HCC group. (I) Gene mutations in the WCH-NonHBV-HCC group and TCGA-Alcol-HCC group. The q values for gene mutations are compared among different groups. Gene mutations with q values <0.1 were deemed as significant. The position of the dotted line is the cutoffs of the q value.