Research Paper Volume 13, Issue 8 pp 11629—11645

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

FTO overexpression reversed the suppressed cell proliferation, invasion and migration capability caused by hsa

Figure 7. FTO overexpression reversed the suppressed cell proliferation, invasion and migration capability caused by hsa_circ_0072309 loss. (A) Cell proliferation assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (B) Transwell assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (C) Wound-healing assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (D) Cell proliferation assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. (E) Transwell assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. (F) Wound-healing assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. Quantitative results are indicated in the right panel (B–C, E–F). Two-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01.