Research Paper Volume 13, Issue 8 pp 11629—11645

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

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Figure 7. FTO overexpression reversed the suppressed cell proliferation, invasion and migration capability caused by hsa_circ_0072309 loss. (A) Cell proliferation assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (B) Transwell assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (C) Wound-healing assays of control and hsa_circ_0072309-KD H1975 cells with or without FTO overexpression. (D) Cell proliferation assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. (E) Transwell assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. (F) Wound-healing assays of control and hsa_circ_0072309-KD H1650 cells with or without FTO overexpression. Quantitative results are indicated in the right panel (B–C, E–F). Two-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01.