Research Paper Volume 13, Issue 8 pp 11678—11695

Piccolo is essential for the maintenance of mouse retina but not cochlear hair cell function

Expression levels of synaptic ribbon-related proteins in Piccolo-/- mice. (A) Relative mRNA levels of ribbon-related genes in Piccolo-/- and wild type (WT) mice. n=5. (B) Western blot analysis of CtBP2 in Piccolo-/- and WT mice (GADPH was used as the loading control.) n=5. (C) Relative CtBP2 band intensities normalized to GADPH. n=5. (D) Relative mRNA levels of Bassoon in Piccolo-/- and WT mice. n=5. (E) Western blot analysis of Bassoon in Piccolo-/- and WT mice. (GADPH was used as the loading control.) n=5. (F) Relative Bassoon band intensities normalized to GADPH. Data represent the means ± SD. **P

Figure 8. Expression levels of synaptic ribbon-related proteins in Piccolo-/- mice. (A) Relative mRNA levels of ribbon-related genes in Piccolo-/- and wild type (WT) mice. n=5. (B) Western blot analysis of CtBP2 in Piccolo-/- and WT mice (GADPH was used as the loading control.) n=5. (C) Relative CtBP2 band intensities normalized to GADPH. n=5. (D) Relative mRNA levels of Bassoon in Piccolo-/- and WT mice. n=5. (E) Western blot analysis of Bassoon in Piccolo-/- and WT mice. (GADPH was used as the loading control.) n=5. (F) Relative Bassoon band intensities normalized to GADPH. Data represent the means ± SD. **P < 0.01, ***P < 0.001, by two-tailed Student’s t test, n=5.