Figure 1. Definition of clinically improved and non-improved. a: including lesion areas absorbed, improved with reduced extent, decreased density and/or formation of fibrotic stripes. b: including lesion areas enlarged, and/or with increased density. c: means at least the last twice results of viral nucleic acid tests must be negative. d: means at least one of the last two results of viral nucleic acid test is still positive. e: we did not found patients like this, so remove this type.