Research Paper Volume 13, Issue 8 pp 11762—11773

Characterization of murine mammary stem/progenitor cells in a D-galactose-induced aging model

D-galactose alters luminal progenitor cell differentiation in vitro. (A) Representative immunofluorescence images showing distinct colonies formed by luminal progenitor cells on plates pre-seeded with irradiated NIH-3T3 fibroblasts; (B) Bar graph shows the distribution of different types of colonies formed by luminal progenitor from control and D-galactose-treated mice (> 20 colonies per animal × 3 animals). K14: basal cell marker keratin 14; K8: luminal cell marker keratin 8.

Figure 5. D-galactose alters luminal progenitor cell differentiation in vitro. (A) Representative immunofluorescence images showing distinct colonies formed by luminal progenitor cells on plates pre-seeded with irradiated NIH-3T3 fibroblasts; (B) Bar graph shows the distribution of different types of colonies formed by luminal progenitor from control and D-galactose-treated mice (> 20 colonies per animal × 3 animals). K14: basal cell marker keratin 14; K8: luminal cell marker keratin 8.