Research Paper Volume 13, Issue 10 pp 13585—13614

Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

Hemodynamics assessment of left ventricular function. (A) Representative recordings of left ventricular (LV) pressure and pressure change rate (dp/dt). (B) LV systolic pressure. (C) LV end-diastolic pressure. (D) Maximum increasing rate of LV pressure (dp/dt max). (E) Maximum descending rate of the LV pressure (dp/dt min). (F) LV contractility index (dp/dt max divided by the pressure at the time of dp/dt max). (G) Exponential time constant of relaxation (Tau). *P #P n = 6–10 at various time point.

Figure 5. Hemodynamics assessment of left ventricular function. (A) Representative recordings of left ventricular (LV) pressure and pressure change rate (dp/dt). (B) LV systolic pressure. (C) LV end-diastolic pressure. (D) Maximum increasing rate of LV pressure (dp/dt max). (E) Maximum descending rate of the LV pressure (dp/dt min). (F) LV contractility index (dp/dt max divided by the pressure at the time of dp/dt max). (G) Exponential time constant of relaxation (Tau). *P < 0.05 compared with the sham group. #P < 0.05 compared with the prior time point in the MI group. n = 6–10 at various time point.