Research Paper Volume 13, Issue 10 pp 13585—13614

Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

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Figure 5. Hemodynamics assessment of left ventricular function. (A) Representative recordings of left ventricular (LV) pressure and pressure change rate (dp/dt). (B) LV systolic pressure. (C) LV end-diastolic pressure. (D) Maximum increasing rate of LV pressure (dp/dt max). (E) Maximum descending rate of the LV pressure (dp/dt min). (F) LV contractility index (dp/dt max divided by the pressure at the time of dp/dt max). (G) Exponential time constant of relaxation (Tau). *P < 0.05 compared with the sham group. #P < 0.05 compared with the prior time point in the MI group. n = 6–10 at various time point.