Figure 6. Cardiac remodeling validated by morphological and histological analysis. (A) Representative images of whole hearts and cross sections of hearts stained with hematoxylin-eosin staining (HE) and Masson's trichrome staining from different time points (scale bar = 2 mm). (B) Heart weight to body weight ratio (HW/BW). (C) Heart weight to tibia length ratio (HW/TL). (D) Lung weight to body weight ratio (LW/BW). (E) Lung weight to tibia length ratio (LW/TL); n = 8–10 at different time points. (F) Expression of the gene encoding ANP (atrial natrium peptide). (G) Expression of the gene encoding α-MHC (α-myosin heavy chain, Myh6). (H) Expression of β-MHC (Myh7); n = 6 at each time point. *P < 0.05 vs. the corresponding time point in the sham group. #P < 0.05 compared with the prior time point in the MI group.