Research Paper Volume 13, Issue 6 pp 7800—7827

Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress

Analysis of NKT subpopulations in PBMCs from 2 m/o, 14 m/o and 14 m/o + APAP mice by flow cytometry. (A) Percentage of Cd8+ cells from Cd45+Cd3+NK1.1+ cells. (B) Percentage of Cd4+ cells from Cd45+Cd3+NK1.1+ cells. (C) Linear regression between NAS score and Cd4+ cells from Cd45+Cd3+NK1.1+ cells in PBMCs. Data are represented as the mean ± S.E.M. (n = 9-14 mice per group). Statistical analysis was performed by Brown-Forsythe and Welch ANOVA test followed by their respective post-hoc test. * P P vs. 2 m/o; ##P ###P vs. 14 m/o.

Figure 7. Analysis of NKT subpopulations in PBMCs from 2 m/o, 14 m/o and 14 m/o + APAP mice by flow cytometry. (A) Percentage of Cd8+ cells from Cd45+Cd3+NK1.1+ cells. (B) Percentage of Cd4+ cells from Cd45+Cd3+NK1.1+ cells. (C) Linear regression between NAS score and Cd4+ cells from Cd45+Cd3+NK1.1+ cells in PBMCs. Data are represented as the mean ± S.E.M. (n = 9-14 mice per group). Statistical analysis was performed by Brown-Forsythe and Welch ANOVA test followed by their respective post-hoc test. * P < 0.05 and ** P < 0.01 vs. 2 m/o; ##P < 0.01 and ###P < 0.001 vs. 14 m/o.