Research Paper Volume 13, Issue 8 pp 11860—11876

Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women

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Figure 2. The genetic landscape of tissue DNA and plasma ctDNA alterations in Chinese breast cancer patients. Green and orange colors represent mutations, and CNV detected in tissue samples, respectively; blue and pink colors represent mutations, and CNV detected in cfDNA samples, respectively. Each column represents one patient. Each row represents one gene. The top bar denotes the number of mutations detected in each patient. The sidebar represents the proportion of patients with a mutation in a certain gene. CNV, copy number variation; ctDNA, circulating tumor-derived DNA; cfDNA, cell-free DNA.