Research Paper Volume 13, Issue 8 pp 11877—11888

Overexpression of microRNA-202-3p in bone marrow mesenchymal stem cells improves cerebral ischemia-reperfusion injury by promoting angiogenesis and inhibiting inflammation

BMSCs overexpressing miR-202-3p can improve CIRI. (A) miR-202-3p was transfected into BMSCs to produce BMSCs that overexpressed miR-202-3p (magnification: 200×). (B) Quantification of miR-202-3p overexpression. (C) MCAO animal model (HE staining) (magnification: 200×). (D–F) Corresponding evaluation index. (*compared with control, #compared with MCAO, +compared with MCAO + BMSCs, p

Figure 2. BMSCs overexpressing miR-202-3p can improve CIRI. (A) miR-202-3p was transfected into BMSCs to produce BMSCs that overexpressed miR-202-3p (magnification: 200×). (B) Quantification of miR-202-3p overexpression. (C) MCAO animal model (HE staining) (magnification: 200×). (DF) Corresponding evaluation index. (*compared with control, #compared with MCAO, +compared with MCAO + BMSCs, p<0.05).