Research Paper Volume 13, Issue 9 pp 12466—12478

Supplementary research on K150del variant of activated protein C

Anti-viral effects of APC derivatives. (A) Western blot analysis of IFIT1, IFITM3, ISG15, OAS1 and RSAD2 antigens in mice lung tissues (n = 4 for each group) after multiple injections with PBS, APC-WT, or APC-DEL. GAPDH antigen was used as the internal control. (B) The intensity value of each band was analyzed using the Image Lab software. The significance level was set at *P P P

Figure 7. Anti-viral effects of APC derivatives. (A) Western blot analysis of IFIT1, IFITM3, ISG15, OAS1 and RSAD2 antigens in mice lung tissues (n = 4 for each group) after multiple injections with PBS, APC-WT, or APC-DEL. GAPDH antigen was used as the internal control. (B) The intensity value of each band was analyzed using the Image Lab software. The significance level was set at *P < 0.05, **P < 0.01 and ***P < 0.001 (compared with the APC-WT group).