Research Paper Volume 13, Issue 8 pp 12067—12085

Expression profile, molecular functions, and prognostic significance of miRNAs in primary colorectal cancer stem cells

pCRCSC-related miRNA signature is an independent prognostic factor for OS in CRC patients. Forest plot summary of multivariate analyses for OS with gender, age, tumor location, tumor stage, MSI status, adjuvant chemoradiotherapy as covariates, and the risk based on pCRCSC-related miRNA signature in the training (A, B) validation cohorts. Squares on the transverse lines represent the hazard ratio (HR), whereas transverse lines represent 95% confidence interval (CI).

Figure 6. pCRCSC-related miRNA signature is an independent prognostic factor for OS in CRC patients. Forest plot summary of multivariate analyses for OS with gender, age, tumor location, tumor stage, MSI status, adjuvant chemoradiotherapy as covariates, and the risk based on pCRCSC-related miRNA signature in the training (A, B) validation cohorts. Squares on the transverse lines represent the hazard ratio (HR), whereas transverse lines represent 95% confidence interval (CI).