Research Paper Volume 13, Issue 9 pp 12552—12564

LncRNA NONMMUT055714 acts as the sponge of microRNA-7684-5p to protect against postoperative cognitive dysfunction

Influence of NONMMUT055714 expression on inflammatory markers, oxidative stress, tau protein phosphorylation, and neuronal apoptosis in primary hippocampal neurons. (A) Differential expression of SORLA, Aβ and P-Tau by Western Blot. (B) Expression of IL-1, IL-6, and TNF-α. (C) Quantitative analyses of MDA, 8-iso-PGF2α, and CAT levels in neurons. (D) Percentage of hippocampal neuron apoptosis by flow cytometry. N = 3 from three independent experiments. Data represented as mean ± SD; * indicates p

Figure 2. Influence of NONMMUT055714 expression on inflammatory markers, oxidative stress, tau protein phosphorylation, and neuronal apoptosis in primary hippocampal neurons. (A) Differential expression of SORLA, Aβ and P-Tau by Western Blot. (B) Expression of IL-1, IL-6, and TNF-α. (C) Quantitative analyses of MDA, 8-iso-PGF2α, and CAT levels in neurons. (D) Percentage of hippocampal neuron apoptosis by flow cytometry. N = 3 from three independent experiments. Data represented as mean ± SD; * indicates p < 0.05.