Research Paper Volume 13, Issue 9 pp 12733—12747

Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

The analysis flow chart of the study. CAS: Carotid atherosclerosis. DEGs: differentially expressed genes. DEseq2: R package for transcriptional sequencing. FC: Fold change. |logFC|>3: The logarithm of the ratio of mRNA expression in CAS patients to that of healthy people is more than 3 times. Adj.p.Val: corrected p-value. PPI: protein-protein interaction. TF enrichment: transcription factor enrichment.

Figure 1. The analysis flow chart of the study. CAS: Carotid atherosclerosis. DEGs: differentially expressed genes. DEseq2: R package for transcriptional sequencing. FC: Fold change. |logFC|>3: The logarithm of the ratio of mRNA expression in CAS patients to that of healthy people is more than 3 times. Adj.p.Val: corrected p-value. PPI: protein-protein interaction. TF enrichment: transcription factor enrichment.