Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

Zhongchen Li; Jiheng Hao; Kun Chen; Qunlong Jiang; Peijian Wang; Xiaohui Xing; Jiyue Wang; Yinjiang Zhang; Yilei Xiao; Liyong Zhang

doi:doi:10.18632/aging.202943

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Research Paper Volume 13, Issue 9 pp 12733—12747

Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

Figure 5. PPI network constructing and hub gene screening of DEGs. (A) PPI network constructed using STRING Online Database contained 1055 nodes and 1883 edges. (B) PPI network was optimized through Cytoscape software. (C) 20 hub genes identified through degree method in cytoHubba. PPI network: protein-protein interaction network.