Research Paper Volume 13, Issue 9 pp 12896—12918

Identification of a novel glycolysis-related gene signature for predicting the prognosis of osteosarcoma patients

Validation of the prognosis risk signature in GSE21257. (A) Kaplan-Meier survival curve of overall survival rate among OS patients from the low-risk group and the high-risk group in GSE21257. Patients in high-risk group had the poorer prognosis. (B) Survival prediction of the risk signature in GSE21257 was assessed by time-dependent receiver operating characteristic (ROC) curve for 1 and 3 years. (C) Risk scores among metastasis and non-metastasis groups in GSE21257. (D) Distribution of risk score in the high-risk group and the low-risk group in GSE21257. (E) Survival status between the high-risk group and the low-risk group in GSE21257. (F) Heatmap of the expression profile of the included glycolysis-related genes in GSE21257.

Figure 5. Validation of the prognosis risk signature in GSE21257. (A) Kaplan-Meier survival curve of overall survival rate among OS patients from the low-risk group and the high-risk group in GSE21257. Patients in high-risk group had the poorer prognosis. (B) Survival prediction of the risk signature in GSE21257 was assessed by time-dependent receiver operating characteristic (ROC) curve for 1 and 3 years. (C) Risk scores among metastasis and non-metastasis groups in GSE21257. (D) Distribution of risk score in the high-risk group and the low-risk group in GSE21257. (E) Survival status between the high-risk group and the low-risk group in GSE21257. (F) Heatmap of the expression profile of the included glycolysis-related genes in GSE21257.