Research Paper Volume 13, Issue 10 pp 13726—13738

Long non-coding RNA FEZF1-AS1 promotes the proliferation and metastasis of hepatocellular carcinoma via targeting miR-107/Wnt/β-catenin axis

FEZF1-AS1 promoted the proliferation and invasion and inhibits the apoptosis of HCC cells. (A) qRT-PCR was used to detect the expression of FEZF1-AS1 after cell transfection with sh-NC, sh-FEZF1-AS1, OE-NC and OE-FEZF1-AS1 or without, *P #P B, C) CCK8 assay was used to determine the proliferation of SNU-398 and SNU-449 cells, *P #P D–F) Flow cytometry was used to test the apoptosis of SNU-398 and SNU-449 cells, *P #P G–I) Transwell chambers were used to assess the invasion of SNU-398 and SNU-449 cells, *P #P

Figure 2. FEZF1-AS1 promoted the proliferation and invasion and inhibits the apoptosis of HCC cells. (A) qRT-PCR was used to detect the expression of FEZF1-AS1 after cell transfection with sh-NC, sh-FEZF1-AS1, OE-NC and OE-FEZF1-AS1 or without, *P < 0.05, #P < 0.05. (B, C) CCK8 assay was used to determine the proliferation of SNU-398 and SNU-449 cells, *P < 0.05, #P < 0.05. (DF) Flow cytometry was used to test the apoptosis of SNU-398 and SNU-449 cells, *P < 0.05, #P < 0.05. (GI) Transwell chambers were used to assess the invasion of SNU-398 and SNU-449 cells, *P < 0.05, #P < 0.05.