Research Paper Volume 13, Issue 9 pp 12929—12954

Prognostic and immunological potential of PPM1G in hepatocellular carcinoma

Correlations of PPM1G expression with the immune infiltration level and immune subtypes in LIHC. (A) PPM1G expression was significantly correlated with tumor purity and the levels of infiltrating B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in LIHC (TIMER). (B) Influence of PPM1G CNV on the levels of infiltrating immune cells in LIHC (TIMER). (C) Distribution of PPM1G expression across immune subtypes in LIHC (TISIDB). The different color plots represent the six immune subtypes (C1: wound healing; C2: IFN-gamma dominant; C3: inflammatory; C4: lymphocyte-depleted; C5: immunologically quiet; and C6: TGF-b dominant).

Figure 10. Correlations of PPM1G expression with the immune infiltration level and immune subtypes in LIHC. (A) PPM1G expression was significantly correlated with tumor purity and the levels of infiltrating B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in LIHC (TIMER). (B) Influence of PPM1G CNV on the levels of infiltrating immune cells in LIHC (TIMER). (C) Distribution of PPM1G expression across immune subtypes in LIHC (TISIDB). The different color plots represent the six immune subtypes (C1: wound healing; C2: IFN-gamma dominant; C3: inflammatory; C4: lymphocyte-depleted; C5: immunologically quiet; and C6: TGF-b dominant).