Research Paper Volume 13, Issue 10 pp 13876—13897

Prognostic value of members of NFAT family for pan-cancer and a prediction model based on NFAT2 in bladder cancer

Construction of overall survival risk score model. (A) LASSO coefficient profiles of the genes associated with the DEGs. (B) Partial likelihood deviance was plotted versus log (Lambda). The vertical dotted line indicates the lambda value with the minimum error and the largest lambda value. (C) Risk scores of the patients in the high (red) and low (green) risk groups. (D) Patients of the validation set from TCGA were divided by risk score into high risk and a low risk groups. OS between two risk groups were analyzed and compared by Kaplan-Meier analysis. Red lines represent the high-risk group samples, and blue lines represent the low-risk group samples. (E) ROC curves in the validation set. The abscissa represents sensitivity, and the ordinate represents specificity.

Figure 10. Construction of overall survival risk score model. (A) LASSO coefficient profiles of the genes associated with the DEGs. (B) Partial likelihood deviance was plotted versus log (Lambda). The vertical dotted line indicates the lambda value with the minimum error and the largest lambda value. (C) Risk scores of the patients in the high (red) and low (green) risk groups. (D) Patients of the validation set from TCGA were divided by risk score into high risk and a low risk groups. OS between two risk groups were analyzed and compared by Kaplan-Meier analysis. Red lines represent the high-risk group samples, and blue lines represent the low-risk group samples. (E) ROC curves in the validation set. The abscissa represents sensitivity, and the ordinate represents specificity.