Research Paper Volume 13, Issue 9 pp 13211—13224

Circular RNA Plek promotes fibrogenic activation by regulating the miR-135b-5p/TGF-βR1 axis after spinal cord injury

Overview of differentially expressed ncRNAs and mRNAs. (A) Overview of the analysis pipeline. (B–D) Hierarchical cluster analysis of significantly upregulated and downregulated ncRNAs and mRNAs. Each column represents a sample and each row represents an ncRNA or mRNA. Red represents high relative expression and blue represents low relative expression. (E–G) Volcano plots were used to visualize differential expression after SCI. The red and blue points represent upregulated and downregulated ncRNAs and mRNAs, respectively, with statistical significance. Significance was defined as p

Figure 1. Overview of differentially expressed ncRNAs and mRNAs. (A) Overview of the analysis pipeline. (BD) Hierarchical cluster analysis of significantly upregulated and downregulated ncRNAs and mRNAs. Each column represents a sample and each row represents an ncRNA or mRNA. Red represents high relative expression and blue represents low relative expression. (EG) Volcano plots were used to visualize differential expression after SCI. The red and blue points represent upregulated and downregulated ncRNAs and mRNAs, respectively, with statistical significance. Significance was defined as p < 0.05.