Figure 8. TRIM14 overexpression enhanced melanoma cell migration and invasion through AKT and STAT3 pathways. After indicated treatment, the migration and invasion abilities of A375 cells were determined using wound-healing assay and Transwell assay, respectively (A–C). The protein expression of MMP2 and MMP9 was determined using western blot (D). Magnification ×100. ***p < 0.001 vs Oe-NC; ##, ###p < 0.01, 0.001 vs Oe-TRIM14.