Research Paper Volume 13, Issue 9 pp 13239—13263

Aging-related genes are potential prognostic biomarkers for patients with gliomas

Aging process leads to inflammation and immune injury, increases genomic instability, epigenetic alteration, aberrant telomeres and affects immune cells infiltration, and reprogram metabolism, which might then promote the occurrence and development of cancer.

Figure 1. Aging process leads to inflammation and immune injury, increases genomic instability, epigenetic alteration, aberrant telomeres and affects immune cells infiltration, and reprogram metabolism, which might then promote the occurrence and development of cancer.