Research Paper Volume 13, Issue 11 pp 14940—14967

Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease

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Figure 3. Identification of the refined hub genes. (A, B) Expression of the hub genes in GSE118553 (A) and GSE48350 (B). (C) ROC analysis of the 6 hub genes in GSE118553 and GSE48350. (D) The intersection of the top 3 genes with the highest AUC value in ROC analysis based on GSE118553 and GSE48350. Data were presented as the mean ± SD in each group. ns, p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.