Research Paper Volume 13, Issue 11 pp 14940—14967

Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease

Identification of the refined hub genes. (A, B) Expression of the hub genes in GSE118553 (A) and GSE48350 (B). (C) ROC analysis of the 6 hub genes in GSE118553 and GSE48350. (D) The intersection of the top 3 genes with the highest AUC value in ROC analysis based on GSE118553 and GSE48350. Data were presented as the mean ± SD in each group. ns, p > 0.05, * p p p p

Figure 3. Identification of the refined hub genes. (A, B) Expression of the hub genes in GSE118553 (A) and GSE48350 (B). (C) ROC analysis of the 6 hub genes in GSE118553 and GSE48350. (D) The intersection of the top 3 genes with the highest AUC value in ROC analysis based on GSE118553 and GSE48350. Data were presented as the mean ± SD in each group. ns, p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.