Research Paper Volume 13, Issue 10 pp 14078—14087

Circular RNA ABCB10 contributes to laryngeal squamous cell carcinoma (LSCC) progression by modulating the miR-588/CXCR4 axis


Figure 5. CircABCB10 contributes to LSCC progression by miR-588/CXCR4 axis. (AD) The AMC-HN-8 and Hep-2 cells were treated control shRNA, circABCB10 shRNA, or co-treated with circABCB10 shRNA and miR-588 inhibitor or pcDNA-CXCR4. (A and B) The cell viability was analyzed by MTT assays in the cells. (C and D) The cell apoptosis was tested by flow cytometry analysis in the cells. Data are presented as mean ± SD. Statistic significant differences were indicated: **P < 0.01.