Research Paper Volume 13, Issue 9 pp 12378—12394

Transcriptomic profile of the mice aging lung is associated with inflammation and apoptosis as important pathways

Differentially expressed pathways and potential transcriptional regulators of lungs from old and young mice. (A) Top 10 ranked high- and down Z-score pathways. (B) Upstream regulators. (C) Transcription regulators. Orange bars represent overexpressed genes; blue bars represent underexpressed genes, all of them at a significant level of p

Figure 1. Differentially expressed pathways and potential transcriptional regulators of lungs from old and young mice. (A) Top 10 ranked high- and down Z-score pathways. (B) Upstream regulators. (C) Transcription regulators. Orange bars represent overexpressed genes; blue bars represent underexpressed genes, all of them at a significant level of p< 0.05. These results were obtained using Ingenuity Pathway Analysis™.