Research Paper Volume 13, Issue 9 pp 12378—12394

Transcriptomic profile of the mice aging lung is associated with inflammation and apoptosis as important pathways

CDKN1a functional network identified using Ingenuity Pathway Analysis™. CDKN1a interaction network overlapping senescence associated pathways. Colored nodes refer to genes found in our dataset (green downregulated; red upregulated). Uncolored nodes were not identified as differentially expressed in our experiment and were integrated into the computationally generated IPA networks.

Figure 4. CDKN1a functional network identified using Ingenuity Pathway Analysis™. CDKN1a interaction network overlapping senescence associated pathways. Colored nodes refer to genes found in our dataset (green downregulated; red upregulated). Uncolored nodes were not identified as differentially expressed in our experiment and were integrated into the computationally generated IPA networks.