Research Paper Volume 13, Issue 10 pp 14234—14257

Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension

GSEA and GSVA of hub genes in the PAH. (A, C, E, G, I) Top 3 KEGG pathways in the high-expression group of single hub genes. (A) ANGPT2; (C) CSF3R; (E) CXCL9; (G) NT5E; (I) FGF7. (B, D, F, H, J) GSVA-derived clustering heatmaps of top 20 differentially expressed pathways for each hub gene. (B) ANGPT2; (D) CSF3R; (F) CXCL9; (H) NT5E; (J) FGF7.

Figure 5. GSEA and GSVA of hub genes in the PAH. (A, C, E, G, I) Top 3 KEGG pathways in the high-expression group of single hub genes. (A) ANGPT2; (C) CSF3R; (E) CXCL9; (G) NT5E; (I) FGF7. (B, D, F, H, J) GSVA-derived clustering heatmaps of top 20 differentially expressed pathways for each hub gene. (B) ANGPT2; (D) CSF3R; (F) CXCL9; (H) NT5E; (J) FGF7.