Research Paper Volume 13, Issue 10 pp 14277—14288

Silencing UCHL3 enhances radio-sensitivity of non-small cell lung cancer cells by inhibiting DNA repair

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Figure 5. UCHL3 knockdown impaired HR repair (A) Schematic diagram of HR reporter system. (B) Analysis of HR repair activity in A549 cells and H460 cells after transfected with sh-NC or sh-UCHL3. (C) Analysis of RAD51 foci in A549 cells transfected with sh-NC and sh-UCHL3 after exposure to radiation. (D) Analysis of RAD51 foci in H460 cells transfected with sh-NC and sh-UCHL3 after exposure to radiation. **P < 0.01.