Research Paper Volume 13, Issue 10 pp 14304—14321

Accumulation of CD45RO+CD8+ T cells is a diagnostic and prognostic biomarker for clear cell renal cell carcinoma

Risk score analysis of Shanghai General Hospital RCC cohort (n = 134). (A, B) The risk score and patient’s distribution were visualized with the best cut-off value 1.058. (C) Heatmap of RNA expression profiles. Rows represent RNAs and clinical traits while columns represent patients. (D) Patients were divided into low-risk (n = 72) and high-risk (n = 62) groups based on the optimal cut-off point. And Kaplan-Meier method was applied to estimate the survival status. (E) To compare the sensitivity and specificity of survival predication, ROC analysis of 3- and 5-year OS was performed based on the risk score.

Figure 8. Risk score analysis of Shanghai General Hospital RCC cohort (n = 134). (A, B) The risk score and patient’s distribution were visualized with the best cut-off value 1.058. (C) Heatmap of RNA expression profiles. Rows represent RNAs and clinical traits while columns represent patients. (D) Patients were divided into low-risk (n = 72) and high-risk (n = 62) groups based on the optimal cut-off point. And Kaplan-Meier method was applied to estimate the survival status. (E) To compare the sensitivity and specificity of survival predication, ROC analysis of 3- and 5-year OS was performed based on the risk score.