Research Paper Volume 13, Issue 10 pp 14342—14354

LncRNA MEG8 promotes TNF-α expression by sponging miR-454-3p in bone-invasive pituitary adenomas

Overexpression of MEG8 promoted tumorigenesis and tumor progression in vivo. (A) Mice models, tumor volume and bone slices. (B) Scanning electron microscope results of bone slices (500x). (C) RT-qPCR analyses measured relative MEG8, miR-454-3p and TNF-α expression levels.

Figure 5. Overexpression of MEG8 promoted tumorigenesis and tumor progression in vivo. (A) Mice models, tumor volume and bone slices. (B) Scanning electron microscope results of bone slices (500x). (C) RT-qPCR analyses measured relative MEG8, miR-454-3p and TNF-α expression levels.