COVID-19 Research Paper Volume 13, Issue 10 pp 13393—13404

Dynamic changes in coagulation parameters and correlation with disease severity and mortality in patients with COVID-19

Kaplan-Meier curves for cumulative rate of survival in patients with different levels of PT (A), FDP (B), and D-dimer (C). Cox regression analysis showed that PT prolonged > 4s (HR = 90; CI% = 20–404; p  10 ULN (HR = 64; CI% = 13–334; p  10 ULN (HR = 48; CI% = 11–214; p

Figure 3. Kaplan-Meier curves for cumulative rate of survival in patients with different levels of PT (A), FDP (B), and D-dimer (C). Cox regression analysis showed that PT prolonged > 4s (HR = 90; CI% = 20–404; p < 0.001), D-dimer > 10 ULN (HR = 64; CI% = 13–334; p < 0.001), and FDP > 10 ULN (HR = 48; CI% = 11–214; p < 0.001) were significantly associated with a higher mortality.