Research Paper Volume 13, Issue 11 pp 15013—15031

ERp44/CG9911 promotes fat storage in Drosophila adipocytes by regulating ER Ca2+ homeostasis


Figure 6. Schematic of CG9911 function in lipolysis. (A) CG9911 was expressed in wild type flies. Under normal condition, with CG9911 expression, ER stress effectors are inhibited by GRP78. (B) CG9911 knockout induced lipolysis in fat cells. Without CG9911 expression (dashed circle), ER stress effectors are active and ER Ca2+ level (a cluster of small circles) is decreased. Lowercase p in a circle means phosphorylation.