Research Paper Volume 13, Issue 11 pp 15078—15099

Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation

Bioinformatics analysis of target proteins of EMO against depression. (A) Venn diagram was used to determine the intersection between the EMO and depression targets. (B) Panther classification categorized target proteins of EMO against depression. The figures next to the pie chart indicate the percentage of the protein in the given functional class. (C) GO classification of targets of EMO against depression at GO level 2 into 3 categories: biological process, molecular function and cellular component.

Figure 3. Bioinformatics analysis of target proteins of EMO against depression. (A) Venn diagram was used to determine the intersection between the EMO and depression targets. (B) Panther classification categorized target proteins of EMO against depression. The figures next to the pie chart indicate the percentage of the protein in the given functional class. (C) GO classification of targets of EMO against depression at GO level 2 into 3 categories: biological process, molecular function and cellular component.