Research Paper Volume 13, Issue 11 pp 15164—15192

Identification and validation of a novel eight mutant-derived long non-coding RNAs signature as a prognostic biomarker for genome instability in low-grade glioma

Verification that the GILncSig is an independent prognostic factor. (A–C) The result of univariate Cox regression showed that the age, grade, diagnostic types of gliomas and GILncSig signature were significant prognostic factors for LGG patients. (B–D) while only the factor of age, diagnostic types and GILncSig signature were also associated with overall survival in the multivariate Cox regression model, indicating that the GILncSig signature was the independent prognostic biomarker for predicting the survival of LGG patients.

Figure 10. Verification that the GILncSig is an independent prognostic factor. (AC) The result of univariate Cox regression showed that the age, grade, diagnostic types of gliomas and GILncSig signature were significant prognostic factors for LGG patients. (BD) while only the factor of age, diagnostic types and GILncSig signature were also associated with overall survival in the multivariate Cox regression model, indicating that the GILncSig signature was the independent prognostic biomarker for predicting the survival of LGG patients.